Protein name:
5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1;AMPKb) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
Function:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Subcellular Location:
N/A
Protein Attributes:
50:
MGNTSSERAA | LDRQGGHKTP | RRDSSGGSKD | GDRPKILMDS | PEDADLFHSE |
100:
EIKAPEKEEF | LAWQHDLEVN | DKAPAQARPT | VFRWTGGGKE | VYLSGSFNNW |
150:
SKLPLTRSHN | NFVAILDLPE | GEHQYKFFVD | GQWTHDPSEP | VVTSQLGTVN |
200:
NVIQVKKTDF | EVFDALMVDS | QKCSDVSELS | SSPPGPYHQE | PYISKPEERF |
250:
KAPPILPPHL | LQVILNKDTG | ISCDPALLPE | PNHVMLNHLY | ALSIKDGVMV |
270:
LSATHRYKKK | YVTTLLYKPI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Pig
Bovine
Mouse
ELISA Kit for Bovine AMPK subunit beta-1
ELISA Kit for Bovine AMPK subunit beta-1
ELISA Kit for Bovine AMPK subunit beta-1
ELISA Kit for Bovine AMPK subunit beta-1
ELISA Kit for Bovine AMPK subunit beta-1
CLIA Kit for Bovine AMPK subunit beta-1
CLIA Kit for Bovine AMPK subunit beta-1
CLIA Kit for Bovine AMPK subunit beta-1
CLIA Kit for Bovine AMPK subunit beta-1
CLIA Kit for Bovine AMPK subunit beta-1
Polyclonal Antibody for Bovine AMPK subunit beta-1
Polyclonal Antibody for Bovine AMPK subunit beta-1
Polyclonal Antibody for Bovine AMPK subunit beta-1
Polyclonal Antibody for Bovine AMPK subunit beta-1
Polyclonal Antibody for Bovine AMPK subunit beta-1
Monoclonal Antibody for Bovine AMPK subunit beta-1
Monoclonal Antibody for Bovine AMPK subunit beta-1
Monoclonal Antibody for Bovine AMPK subunit beta-1
Monoclonal Antibody for Bovine AMPK subunit beta-1
Monoclonal Antibody for Bovine AMPK subunit beta-1
Protein for Bovine AMPK subunit beta-1
Protein for Bovine AMPK subunit beta-1
Protein for Bovine AMPK subunit beta-1
Protein for Bovine AMPK subunit beta-1
Protein for Bovine AMPK subunit beta-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Thymus .